Corneal Transplant Surgery In Delhi

Corneal Transplant Surgery In Delhi

Restoring Clarity. One Layer at a Time.
Full Spectrum of Modern Keratoplasty — PK, DALK & DSAEK.

19+

Years of Excellence

10K+

Successful Surgeries

98.5%

Success Rate

4.9/5

(2k+ Reviews, Google)

WHY CHOOSE NETRAM

Advanced Corneal Care Rooted in Trust and Excellence

Full Spectrum of Keratoplasty — PK, DALK & DSAEK

We offer all three major keratoplasty procedures. Your procedure is chosen based on which corneal layers are diseased — maximising outcomes while minimising the risk of rejection.

Fellowship-Trained Corneal Surgeon

Dr. Anchal Gupta completed a dedicated Fellowship in Cornea and Refractive Surgery at the Venu Eye Institute, Delhi. Every keratoplasty is personally performed by her, not delegated.

Lamellar Surgery First — Lower Rejection, Faster Recovery

Where clinically appropriate, we prefer DALK or DSAEK over full-thickness PK. Lamellar techniques replace only the diseased corneal layer — significantly reducing rejection risk.

Combined Surgery When Needed

We offer combined Keratoplasty with Cataract Surgery and Keratoplasty with Glaucoma Surgery for patients who require simultaneous treatment of multiple conditions.

Registered Eye Bank Access — NOTTO Network

Donor corneal tissue is procured through registered eye bank facilities connected to the National Organ and Tissue Transplant Organisation (NOTTO) network. All tissue undergoes mandatory screening.

Cashless & Insurance Empanelled

Keratoplasty is covered under many major health insurance policies. We assist with cashless claims and prior authorisation. EMI options available.

Diagnosed with Corneal Disease? We Can Help.

Diagnosed with Corneal Disease? We Can Help.

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TREATMENT OVERVIEW

Understanding Corneal Transplant (Keratoplasty)

What is a Corneal Transplant?

A corneal transplant — also called keratoplasty or corneal graft — is a surgical procedure in which a diseased, scarred, or damaged cornea is replaced with healthy donor corneal tissue from a deceased human donor. The cornea is the clear, dome-shaped front surface of the eye that contributes approximately 65–70% of the eye's total focusing power.

Why is it needed

When the cornea becomes permanently cloudy, scarred, irregularly shaped, or structurally compromised — from infection, injury, dystrophy, or degeneration — it can no longer transmit clear images to the retina. Glasses and contact lenses cannot correct this. A corneal transplant replaces the damaged tissue with healthy donor tissue, restoring clarity and vision.

Modern approach

Today, surgery is guided by the principle of replacing only the diseased corneal layer rather than the entire cornea. DALK replaces the front 95% of the cornea (anterior layers), preserving the patient's own endothelium. DSAEK replaces only the back layer (endothelium), preserving the patient's healthy anterior cornea. Full-thickness PK replaces the entire cornea and is reserved for conditions affecting all layers.

Donor tissue

All corneal tissue used at Netram is procured from registered eye banks, screened for transmissible infections, evaluated for endothelial cell count (minimum 2000 cells/mm2), and assessed by slit-lamp before surgical use. Corneal tissue does not require blood group matching.

Corneal Diseases That Require Keratoplasty

Keratoconus

A progressive corneal disease in which the normally dome-shaped cornea gradually thins and bulges outward into a cone shape, causing severe distortion, myopia, and astigmatism, usually beginning in the teens to 20s. A transplant is needed when keratoconus progresses beyond what glasses or contact lenses, including scleral lenses, can correct, or when the cornea becomes too thin and irregular for contact lens wear. DALK is the procedure of choice because the endothelium remains healthy, eliminating endothelial rejection risk and offering excellent long-term graft survival. Most patients achieve very good corrected vision, though glasses or rigid contact lenses may still be needed.

Fuchs' Endothelial Dystrophy

An inherited degenerative disease in which the endothelial pump cells progressively die, causing corneal oedema and loss of clarity. It is often bilateral and slowly progressive, with early morning blur that later becomes persistent cloudiness and, in advanced stages, painful bullae. DSAEK is the procedure of choice because only the endothelium is diseased while the anterior cornea remains healthy. It replaces only the back layer, allows faster recovery than PK, and carries a lower rejection risk, with most patients recovering useful vision within 3-6 months.

Pseudophakic Bullous Keratopathy (PBK)

Corneal oedema and bullae formation following cataract surgery due to endothelial cell loss from the surgery itself, phototoxicity, or prior endothelial compromise, resulting in a painful, cloudy cornea. DSAEK is usually preferred because it replaces the damaged endothelium with a healthy donor lenticule while preserving the rest of the cornea. If there is significant anterior scarring, full-thickness PK may be required instead.

Corneal Scarring from Infection or Injury

Severe corneal ulcers from bacterial, fungal, viral, or Acanthamoeba keratitis, along with chemical burns or penetrating trauma, can leave dense stromal scars that permanently block vision even after the active disease resolves. DALK is suitable for stromal scars when the endothelium is intact, while PK is needed for scars involving all layers, perforations, or extensive vascularised scars. Timing matters, and elective transplantation is generally planned only after the eye has remained infection-free and quiet for several months.

Corneal Dystrophies

Corneal dystrophies such as granular, lattice, and macular dystrophy progressively affect the corneal stroma and can eventually reduce vision enough to require transplantation. DALK is preferred for anterior and stromal dystrophies because it preserves healthy endothelium, while PK is used when deeper or full-thickness involvement is present. Recurrence of dystrophy in the donor graft remains possible, especially in granular dystrophy, and some patients may need repeat transplantation years later.

Failed Previous Corneal Graft (Regraft)

A previously transplanted cornea can fail because of rejection, endothelial failure, or recurrence of the original disease, and these regraft cases carry higher risk than primary transplantation. The next procedure depends on why the earlier graft failed: endothelial failure of a PK or DALK graft may be managed with DSAEK, while complete graft failure usually requires repeat PK. Careful evaluation of the cause of failure is essential before planning further surgery.

OUR APPROACH

How We Choose the Right Keratoplasty for Your Eye

Corneal transplantation is not a single surgery. At Netram, the procedure is selected based on which corneal layers are diseased, whether glaucoma or cataract also needs surgical treatment, and which approach offers the best balance of graft survival, visual recovery, and long-term safety.

  • DALK (Deep Anterior Lamellar Keratoplasty): Replaces the front 95% of the cornea while preserving healthy endothelium. Best for keratoconus, anterior scars, and stromal dystrophies. Its key advantage is zero endothelial rejection risk with strong long-term graft survival.

  • DSAEK (Descemet Stripping Automated Endothelial Keratoplasty): Replaces only the diseased endothelial layer and keeps the front of the cornea intact. Best for Fuchs' dystrophy and pseudophakic bullous keratopathy. It offers a sutureless small-incision approach with faster recovery and lower rejection risk than PK.

  • Penetrating Keratoplasty (PK): A full-thickness transplant that replaces all corneal layers. It is used for full-thickness scars, perforations, severe infections, and failed lamellar grafts when partial-thickness surgery is not suitable. Recovery is longer, and long-term steroids plus suture management are essential.

  • Keratoplasty with Glaucoma Surgery: A combined procedure for patients who need both corneal transplantation and surgical pressure control. It may be paired with trabeculectomy or tube surgery in the same session. The main goal is to protect the graft by controlling intraocular pressure at the time of transplant.

  • Keratoplasty with Cataract Surgery: A combined triple procedure for patients with both corneal disease and a visually significant cataract. PK or DSAEK is performed with phacoemulsification and IOL implantation in one session. This reduces the number of surgeries and avoids later cataract surgery through a grafted cornea.

Have Questions about Corneal Transplant? We respond <10 min.

Have Questions about Corneal Transplant?We respond <10 min.

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Netram Eye Foundation

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Hi there! Welcome to Netram Eye Foundation.

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MEET YOUR SURGEON

Your Vision in the Hands of Excellence

Dr. Anchal Gupta

Dr. Anchal Gupta

Fellowship in Cornea & Refractive Surgery

Achievements & Highlights

  • Expert in Cataract, Refractive (LASIK) & Cornea Procedures.

  • Among the fastest surgeon in India.

  • Thousands of successful vision correction surgeries.

  • Winner of many prestigious awards.

  • Known for precision, empathy, and ethical care.

19+

Years
Of Experience

2.5L+

Successful Procedures

7+

Areas of Surgical Expertise

"A corneal transplant gives someone their world back. It is one of the most technically demanding procedures I perform — and one of the most rewarding. The day a patient reads 6/12 for the first time after a DALK is a day I never take for granted."

CORNEAL TRANSPLANT PROTOCOLS — EVERYTHING YOU NEED TO KNOW

Complete Treatment Breakdown

Corneal transplantation is not a single surgery. At Netram, the procedure is selected based on which corneal layers are diseased, whether glaucoma or cataract also needs surgical treatment, and which approach offers the best balance of graft survival, visual recovery, and long-term safety.

Netram Corneal Transplant Surgery — Complete Pricing Summary

ProcedureIndication / DescriptionPrice at Netram
DALK (Deep Anterior Lamellar Keratoplasty)Keratoconus, anterior stromal scars, stromal dystrophies — endothelium preserved₹1,00,000 per eye
DSAEK (Descemet Stripping Automated Endothelial Keratoplasty)Fuchs' dystrophy, pseudophakic bullous keratopathy — anterior cornea preserved₹1,02,000 per eye
Keratoplasty Surgery (Penetrating Keratoplasty — PK)Full-thickness transplant — all-layer disease, perforations, failed lamellar grafts₹60,000 per eye
Keratoplasty with Glaucoma SurgeryCombined PK/DSAEK + trabeculectomy or tube shunt for concurrent glaucoma₹75,000 per eye
Keratoplasty with Cataract Surgery (Triple Procedure)Combined PK/DSAEK + phaco + IOL implantation₹75,000 per eye

PK vs DALK vs DSAEK — Complete Comparison

Every keratoplasty technique has distinct advantages and limitations. Here is a comprehensive side-by-side comparison to help you understand the differences before your consultation.

ParameterPK (Penetrating Keratoplasty)DALK (Deep Anterior Lamellar)DSAEK (Endothelial)
Layers replacedAll 5 layers (full thickness)Anterior 95% (stroma + above)Posterior 5% (endothelium only)
Patient's endotheliumReplaced with donorPreserved — patient's ownReplaced with donor lenticule
Best indicationAll-layer disease, perforations, failed lamellar graftsKeratoconus, anterior stromal scarsFuchs' dystrophy, PBK
Incision size7.0–8.5mm open-sky trephination7.0–8.5mm + partial dissection3–5mm self-sealing
Sutures requiredYes — 16 interrupted or runningYes — 16 interrupted or runningNo sutures (air bubble fixation)
Rejection risk~10% cumulative at 5 yrsNear zero (no endothelium transplanted)Lower than PK; ~5–8% at 5 yrs
Visual recovery12–18 months6–12 months1–3 months
Final vision qualityVariable — astigmatism commonExcellent — matches or exceeds PKGood; slightly reduced contrast vs DMEK
Astigmatism post-opHigh — suture-dependentModerate — suture-dependentMinimal
Globe strength post-opReduced — scar at wound marginSlightly reducedFull strength — minimal incision
Graft survival (5 yr)70–90% (low-risk cases)95%+ (endothelium preserved)90–95%
Price at Netram₹60,000 per eye₹1,00,000 per eye₹1,02,000 per eye

Corneal Graft Rejection — What You Must Know

Corneal graft rejection is the most important long-term risk after keratoplasty. Understanding it, recognising it early, and responding immediately are the three things that determine whether your graft survives.

What is rejection? The immune system recognises the donor corneal tissue as foreign and mounts an inflammatory response to destroy it. This is called an allograft rejection episode. It is not the same as infection. It can occur weeks, months, or even years after surgery.

How common is it? In PK, cumulative rejection occurs in approximately 10% of cases at 5 years. In DALK, endothelial rejection is eliminated (the endothelium is the patient's own). In DSAEK, rejection occurs in approximately 5–8% — less than PK because less foreign tissue is transplanted.

Warning signs — RSVP: Redness, Sensitivity to light, Vision deterioration, Pain. If you experience any of these — particularly after a period of clear vision — contact us the same day. Every hour matters. Do not wait for a routine appointment.

Treatment: Immediate intensive topical steroids (prednisolone acetate 1% hourly) and urgent review. Most early rejection episodes can be reversed if treated promptly. Late or missed rejections lead to graft failure.

Prevention: Lifelong topical steroid drops (tapered over years). Avoid eye trauma. Report any red eye or vision change immediately. Do not stop drops without consulting your corneal surgeon — even years after surgery.

Emergency Contact If you notice sudden redness, light sensitivity, or vision loss in your grafted eye — call Netram Eye Foundation immediately on +91 93199 09455. This is a same-day emergency. Do not delay.

THE COMPLETE TREATMENT JOURNEY

Guiding You Through Every Stage

From your first corneal evaluation to your final suture removal — we guide you through every step of the keratoplasty journey with complete transparency about what to expect, when, and why.

PRE-OP step 1 of 4

First VisitStep 1

Corneal Assessment

Pentacam corneal topography, specular microscopy (endothelial cell count), pachymetry, refraction, slit-lamp, and retinal assessment. Corneal diagnosis confirmed, procedure selected, and patient counselled.

2–8 WeeksStep 2

Eye Bank Tissue Request

Donor tissue request placed with registered eye bank. Waiting time for suitable donor tissue varies — typically 2–8 weeks. Tissue is screened for endothelial count, serology, and slit-lamp quality before dispatch.

1–3 Days PriorStep 3

Pre-Op Investigations

CBC, blood sugar, blood pressure, ECG (if age > 40 or general anaesthesia). Any active surface infection treated and resolved. Topical antibiotic drops started.

Day PriorStep 4

Preparation

Stop contact lens wear. Arrange companion and transport. Peribulbar block planned — no eating for 4 hours if sedation used. Consent signed at pre-op visit.

TESTIMONIALS

Real Patients, Life-Changing Results

Sonu Kashyap avatar

I’m very thankful to Dr. Anchal Gupta for my successful eye operation. She explained the full process clearly, built my confidence, and made me feel genuinely cared for throughout....

Sonu Kashyap

Eye Surgery Review

Prakash Chetri

Cataract Surgery

Shafiya Meditrip avatar

One month after LASIK, my vision is much clearer at 6/4, beyond expectations. Thank you to Dr. Anchal and the team for such a smooth and reassuring experience....

Shafiya Meditrip

LASIK Review

Ritika Kaushal

LASIK Surgery

Akshita Yadav avatar

I had ICL surgery at Netram and felt supported from consultation to follow-up. Dr. Anchal Gupta and Dr. Neha Sharma explained everything patiently and made the whole journey comfortable and reassuring....

Akshita Yadav

ICL Surgery Review

Subhankar

LASIK Surgery

ALL YOUR QUESTIONS ANSWERED

Frequently Asked Questions About Corneal Transplant

What is corneal transplant surgery and is it safe?

Corneal transplantation (keratoplasty) replaces a diseased or scarred cornea with healthy donor tissue from a deceased human donor. It is one of the oldest, most studied, and most successful organ transplant procedures in medicine — with 5-year graft survival rates of 70–95% depending on the technique and indication. At Netram, we are fellowship-trained in corneal surgery and offer the full range of modern lamellar and full-thickness techniques.

What is the difference between PK, DALK, and DSAEK?

PK (Penetrating Keratoplasty) replaces all five layers of the cornea and is used when disease affects all layers. DALK (Deep Anterior Lamellar Keratoplasty) replaces only the front 95% and preserves the patient's own endothelium — eliminating endothelial rejection risk. Best for keratoconus and stromal scars. DSAEK replaces only the innermost endothelial layer through a tiny incision — best for Fuchs' dystrophy and bullous keratopathy. The right choice depends entirely on which corneal layers are diseased in your eye.

Do I need blood group matching for a corneal transplant?

No — corneal tissue does not require blood group or HLA matching. This is one of the unique immunological privileges of the cornea, which lacks blood vessels. Donor tissue is screened for infectious diseases (HIV, Hepatitis B and C, syphilis) and evaluated for endothelial cell quality, but no blood type compatibility is needed.

How long does it take to recover vision after a corneal transplant?

Recovery depends entirely on the technique. DSAEK patients often notice improvement within 1–3 months and reach stable vision at 3–6 months. DALK patients typically see gradual improvement over 6–12 months, with final acuity stabilising at 12–18 months after suture removal. PK patients have the longest recovery — 12–18 months. Glasses or rigid contact lenses are often needed after surgery to optimise final corrected visual acuity.

What is graft rejection and how do I prevent it?

Rejection occurs when the immune system recognises the donor cornea as foreign and attacks it. Warning signs are the RSVP symptoms: Redness, Sensitivity to light, Vision deterioration, and Pain. If you experience any of these, contact us the same day — early treatment with intensive steroid drops reverses most rejection episodes. Prevention requires lifelong topical steroid drops (on a slow taper), protecting the eye from injury, and immediate reporting of any red eye or vision change. Never stop your drops without consulting your surgeon.

How long do I need to use eye drops after corneal transplant?

Topical steroid drops are the cornerstone of rejection prophylaxis after keratoplasty. After PK and DSAEK, steroids are continued long-term — often for years — on a very slow taper. After DALK, the taper may be faster since endothelial rejection is not a risk. Antibiotic drops are used for the first 4–6 weeks post-operatively. Your drop schedule will be tailored based on your specific procedure and graft health at follow-up visits.

Can I wear contact lenses after a corneal transplant?

Rigid gas-permeable (RGP) or scleral contact lenses are often the best way to optimise vision after PK and DALK — where post-operative astigmatism is common. Soft contact lenses are generally not effective on an irregular post-keratoplasty cornea. Lens fitting after corneal transplantation requires specialist expertise. We provide corneal topography-guided contact lens fitting at Netram. After DSAEK, soft or toric soft lenses may be sufficient as astigmatism is minimal.

What are the costs of corneal transplant at Netram Eye Foundation?

Our current pricing: DALK — ₹1,00,000 per eye. DSAEK — ₹1,02,000 per eye. Penetrating Keratoplasty (PK) — ₹60,000 per eye. Keratoplasty with Glaucoma Surgery — ₹75,000 per eye. Keratoplasty with Cataract Surgery (Triple Procedure) — ₹75,000 per eye. These prices are for the surgical procedure. Donor tissue (eye bank), consumables, and post-operative medications are additional. Cashless insurance and EMI options are available. Please contact us for a personalised cost estimate.

What happens if my corneal graft fails?

A failed graft can often be treated with a repeat transplantation (regraft). DSAEK failure (endothelial) can be managed with re-DSAEK or DMEK. DALK failure due to endothelial decompensation can be managed with DSAEK, preserving the previously transplanted anterior donor stroma. Regraft surgery carries a higher rejection risk than primary grafts, and outcomes vary based on the cause of failure and the state of the eye. We manage complex regraft cases at Netram.

Is eye donation in India easy? How do I donate my eyes?

Eye donation in India is a simple, noble act that can restore vision for two people. You can pledge your eyes through the National Eye Bank at any time during your life. After death, the family must call the eye bank within 6 hours. Eyes are harvested at home or at the hospital — no disfigurement. The face looks completely normal. For eye bank contact in Delhi, call AIIMS Eye Bank or the local NOTTO-registered eye bank. At Netram, we can connect you with the process. One pair of eyes can give sight to two people — please consider this gift.

Still have questions? Our team is available on WhatsApp — we respond in under 10 minutes.

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